Peter C Adamson Selected Research

Methotrexate (Mexate)

12/2011	Preclinical evaluation of pemetrexed in pediatric solid tumors.
5/2010	Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias.
6/2006	Understanding and managing methotrexate nephrotoxicity.
4/2005	The bioavailability of oral methotrexate in children with inflammatory bowel disease.
10/2004	Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.
5/2004	High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma.

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Peter C Adamson Research Topics

Disease

70	Neoplasms (Cancer) 01/2021 - 11/2003
15	Neuroblastoma 01/2021 - 02/2004
11	Leukemia 01/2020 - 03/2007
11	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2018 - 09/2007
10	Neutropenia 05/2013 - 11/2005
9	Thrombocytopenia (Thrombopenia) 05/2014 - 12/2004
8	Ewing Sarcoma (Sarcoma, Ewing) 01/2014 - 11/2006
7	Fatigue 02/2013 - 11/2006
4	Lymphoma (Lymphomas) 11/2021 - 09/2007
4	Sarcoma (Soft Tissue Sarcoma) 01/2016 - 11/2006
4	Nausea 02/2013 - 01/2008
4	Hypertension (High Blood Pressure) 11/2012 - 07/2006
4	Diarrhea 11/2012 - 04/2009
4	Rhabdomyosarcoma 03/2012 - 01/2008
4	Osteosarcoma (Osteogenic Sarcoma) 01/2010 - 05/2004
4	Medulloblastoma 03/2008 - 12/2004
3	Absence Epilepsy (Childhood Absence Epilepsy) 01/2023 - 03/2010
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2015 - 11/2007
3	Anorexia 05/2014 - 04/2010
3	Vomiting 02/2013 - 01/2008
3	Glioma (Gliomas) 08/2011 - 08/2008
3	Hypokalemia 03/2011 - 04/2009
3	Headache (Headaches) 12/2010 - 01/2008
3	Body Weight (Weight, Body) 05/2010 - 11/2005
3	Abdominal Pain (Pain, Abdominal) 04/2010 - 01/2008
3	Wilms Tumor (Wilm's Tumor) 01/2010 - 10/2007
3	Hypotension (Low Blood Pressure) 03/2007 - 12/2004
2	Disease Progression 01/2021 - 09/2005
2	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 12/2020 - 05/2013
2	Febrile Neutropenia 01/2020 - 03/2007
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2018 - 02/2009
2	Residual Neoplasm 07/2015 - 12/2011
2	Hematologic Neoplasms (Hematological Malignancy) 07/2015 - 02/2011
2	Philadelphia Chromosome 05/2015 - 03/2011
2	Hyperglycemia 02/2013 - 01/2008
2	Anemia 02/2013 - 10/2007
2	Exanthema (Rash) 02/2013 - 11/2012
2	Seizures (Absence Seizure) 01/2013 - 10/2004
2	Synovial Sarcoma (Synovioma) 01/2010 - 02/2008
2	Candidiasis (Moniliasis) 08/2009 - 11/2005
2	Primitive Neuroectodermal Tumors (PNET) 11/2006 - 12/2004
2	Hypocalcemia 08/2006 - 12/2004
2	Critical Illness (Critically Ill) 11/2004 - 11/2003
1	Diffuse Intrinsic Pontine Glioma 01/2022

Drug/Important Bio-Agent (IBA)

6	Vincristine (Oncovin)FDA LinkGeneric 11/2021 - 12/2004
6	Imatinib Mesylate (Gleevec)FDA Link 01/2018 - 01/2007
6	Methotrexate (Mexate)FDA LinkGeneric 12/2011 - 05/2004
5	Temozolomide (Temodar)FDA LinkGeneric 05/2014 - 11/2007
4	Valproic Acid (Depakote)FDA LinkGeneric 01/2023 - 03/2010
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2021 - 04/2007
4	ABT751IBA 06/2014 - 08/2006
4	Irinotecan (Camptosar)FDA LinkGeneric 05/2014 - 10/2007
4	RetinoidsIBA 01/2014 - 01/2006
4	FenretinideIBA 01/2014 - 01/2006
4	Pemetrexed (MTA)FDA Link 02/2013 - 04/2007
3	Lamotrigine (Lamictal)FDA LinkGeneric 01/2023 - 03/2010
3	Ethosuximide (Zarontin)FDA LinkGeneric 01/2023 - 03/2010
3	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2021 - 04/2007
3	Rituximab (Mabthera)FDA Link 11/2021 - 09/2007
3	CrizotinibIBA 01/2021 - 05/2013
3	Proteins (Proteins, Gene)FDA Link 11/2020 - 12/2010
3	Tyrosine Kinase InhibitorsIBA 01/2018 - 09/2005
3	Alanine Transaminase (SGPT)IBA 05/2014 - 11/2012
3	Topotecan (Hycamtin)FDA LinkGeneric 01/2014 - 11/2006
3	Transaminases (Aminotransferases)IBA 08/2011 - 01/2008
3	esmolol (Brevibloc)FDA LinkGeneric 08/2008 - 11/2003
3	Dactinomycin (Actinomycin)FDA LinkGeneric 01/2008 - 04/2006
2	Histone Deacetylase InhibitorsIBA 01/2022 - 08/2006
2	Vorinostat FDA Link 01/2022 - 08/2010
2	Anaplastic Lymphoma KinaseIBA 01/2021 - 05/2013
2	Carboplatin (JM8)FDA LinkGeneric 01/2019 - 08/2011
2	Asparaginase (Elspar)FDA Link 01/2018 - 12/2014
2	epratuzumabIBA 07/2015 - 08/2008
2	cixutumumabIBA 03/2014 - 01/2012
2	Isotretinoin (Accutane)FDA LinkGeneric 01/2014 - 12/2011
2	Cytotoxins (Cytolysins)IBA 01/2014 - 04/2006
2	Cisplatin (Platino)FDA LinkGeneric 01/2014 - 12/2004
2	EnzymesIBA 05/2013 - 04/2009
2	MLN 8237IBA 11/2012 - 09/2010
2	Alkaline PhosphataseIBA 11/2012 - 08/2011
2	Sunitinib (Sutent)FDA Link 04/2012 - 08/2011
2	lissamine rhodamine B (sulforhodamine B)IBA 12/2011 - 05/2010
2	Phosphotransferases (Kinase)IBA 12/2011 - 01/2007
2	CreatinineIBA 03/2011 - 03/2007
2	dimemorfan (AT 17)IBA 12/2010 - 08/2006
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 09/2010 - 04/2009
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 08/2010 - 10/2007
2	Lipase (Acid Lipase)FDA Link 04/2009 - 03/2008
2	Amylases FDA Link 04/2009 - 03/2008
2	Caspofungin (Cancidas)FDA Link 04/2009 - 11/2005
2	ErbB Receptors (EGF Receptor)IBA 10/2008 - 09/2005
2	Monoclonal AntibodiesIBA 08/2008 - 03/2006
2	Lomustine (CCNU)FDA Link 08/2008 - 12/2004
2	Tubulin ModulatorsIBA 02/2008 - 08/2006
2	Proteasome InhibitorsIBA 03/2007 - 12/2004
2	Bortezomib (Velcade)FDA Link 03/2007 - 12/2004

Therapy/Procedure

20	Therapeutics 01/2022 - 11/2003
15	Drug Therapy (Chemotherapy) 12/2020 - 11/2003
5	Radiotherapy 01/2022 - 12/2004
3	Intravenous Infusions 02/2013 - 11/2006